Characterization of the Radical-Scavenging Reaction of 2-O-Substituted Ascorbic Acid Derivatives, AA-2G, AA-2P, and AA-2S: A Kinetic and Stoichiometric Study

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چکیده

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Radical scavenging activity against 1,1-diphenyl-2-picrylhydrazyl of ascorbic acid 2-glucoside (AA-2G) and 6-acyl-AA-2G.

The radical scavenging activity of the stable derivatives, which are O-substituted at the C-2 position of ascorbic acid (AA), against 1,1-diphenyl-2-picrylhydrazyl (DPPH) was evaluated in buffer under different pH conditions, and compared with those of AA and alpha-tocopherol. AA was shown to have 50% radical scavenging ability (EC50) at a concentration of 2.2 x 10(-5) M against 0.1 mM DPPH in ...

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Long-term radical scavenging activity of AA-2G and 6-acyl-AA-2G against 1,1-diphenyl-2-picrylhydrazyl.

Stoichiometric evaluation of the radical scavenging activity of O-substituted derivatives at the C-2 position of ascorbic acid (AA) was conducted. Their reaction with a stable radical, 1,1-diphenyl-2-picrylhydrazyl (DPPH), under an acidic condition was assessed by the colorimetric method. 2-O-alpha-D-Glucopyranosyl-L-ascorbic acid (AA-2G) and a series of 6-O-acyl-2-O-alpha-D-glucopyranosyl-L-as...

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Arachidonic Acid (AA, ARA) Derivatives

When it comes to joint pain, it is mostly the cartilage that is inflamed and chronic headaches often result from neural inflammatory processes. Overcoming this pain will often seem impossible. What is little known: Superhormones, which can regulate the hormonal balance of the body, exist – these are eicosanoids, derivatives of arachidonic acid, an omega-6 fatty acid. What effect do the arachido...

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ژورنال

عنوان ژورنال: Biological and Pharmaceutical Bulletin

سال: 2006

ISSN: 0918-6158,1347-5215

DOI: 10.1248/bpb.29.766